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Frans Van de Werf Selected Research

Tenecteplase

1/2020The Second Strategic Reperfusion Early After Myocardial Infarction (STREAM-2) study optimizing pharmacoinvasive reperfusion strategy in older ST-elevation myocardial infarction patients.
1/2017Corrigendum to "Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the Strategic Reperfusion Early After Myocardial infarction trial" [Am Heart J 169/6 (2015) 890-898].
6/2015Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the STrategic Reperfusion Early After Myocardial infarction trial.
4/2013Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
5/2011Intraluminal thrombus in facilitated versus primary percutaneous coronary intervention: an angiographic substudy of the ASSENT-4 PCI (Assessment of the Safety and Efficacy of a New Treatment Strategy with Percutaneous Coronary Intervention) trial.
5/2006Efficacy and safety of unfractionated heparin versus enoxaparin: a pooled analysis of ASSENT-3 and -3 PLUS data.
7/2005Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial.
4/2005Relationship of incorrect dosing of fibrinolytic therapy and clinical outcomes.
4/2005Economic analysis of the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT-3) study: costs of reperfusion strategies in acute myocardial infarction.
8/2004Efficacy and safety of two unfractionated heparin dosing strategies with tenecteplase in acute myocardial infarction (results from Assessment of the Safety and Efficacy of a New Thrombolytic Regimens 2 and 3).
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Frans Van de Werf Research Topics

Disease

111Myocardial Infarction
10/2019 - 01/2002
70Acute Coronary Syndrome
07/2021 - 01/2002
58ST Elevation Myocardial Infarction
01/2021 - 04/2002
51Hemorrhage
01/2020 - 01/2002
32Stroke (Strokes)
10/2019 - 02/2005
28Heart Failure
01/2018 - 05/2002
25Infarction (Infarctions)
01/2018 - 12/2002
14Ischemia
03/2017 - 02/2004
11Thrombosis (Thrombus)
11/2018 - 08/2003
7Type 2 Diabetes Mellitus (MODY)
10/2018 - 07/2015
7Unstable Angina
01/2018 - 07/2002
7Cardiovascular Diseases (Cardiovascular Disease)
01/2018 - 06/2002
7Inflammation (Inflammations)
04/2007 - 05/2004
7Left Ventricular Dysfunction
03/2007 - 08/2003
6Vascular Diseases (Vascular Disease)
11/2020 - 07/2003
5Shock
01/2021 - 01/2007
5Intracranial Hemorrhages (Intracranial Hemorrhage)
01/2020 - 04/2003
5Myocardial Ischemia (Ischemic Heart Diseases)
04/2015 - 07/2006
4Cardiogenic Shock
01/2021 - 04/2007
4Body Weight (Weight, Body)
01/2018 - 07/2003
4Diabetes Mellitus
11/2017 - 08/2006
4Atrial Fibrillation
09/2013 - 10/2006
4Coronary Artery Disease (Coronary Atherosclerosis)
03/2012 - 06/2002
3Chronic Obstructive Pulmonary Disease (COPD)
12/2019 - 12/2015
3Coronary Disease (Coronary Heart Disease)
01/2019 - 04/2006
3Reperfusion Injury
04/2015 - 05/2004
2Non-ST Elevated Myocardial Infarction
12/2019 - 01/2018
2Hemorrhagic Stroke
12/2018 - 12/2017
2Sudden Death
11/2018 - 06/2005
2Hypertension (High Blood Pressure)
11/2017 - 02/2010
2Peripheral Arterial Disease
12/2015 - 10/2014
2Necrosis
07/2013 - 08/2006
2Transient Ischemic Attack
01/2011 - 02/2010
2Ventricular Fibrillation
01/2011 - 12/2008
2Ventricular Tachycardia
01/2011 - 12/2008

Drug/Important Bio-Agent (IBA)

21vorapaxarIBA
12/2018 - 03/2009
19Glycoproteins (Glycoprotein)IBA
01/2018 - 01/2002
17Thrombin Receptors (Thrombin Receptor)IBA
12/2018 - 11/2010
14TenecteplaseFDA Link
01/2020 - 04/2003
14Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2018 - 06/2002
12Eptifibatide (Integrilin)FDA Link
04/2014 - 07/2002
12pexelizumabIBA
07/2012 - 03/2005
10CreatinineIBA
12/2019 - 07/2003
10Enoxaparin (Lovenox)FDA LinkGeneric
07/2013 - 04/2002
9Sitagliptin Phosphate (Januvia)FDA Link
11/2020 - 07/2015
9Heparin (Liquaemin)FDA LinkGeneric
05/2011 - 08/2002
8Valsartan (Vals)FDA Link
06/2009 - 08/2003
7Pharmaceutical PreparationsIBA
01/2021 - 01/2002
7Clopidogrel (Plavix)FDA Link
12/2014 - 04/2008
6Tissue Plasminogen Activator (Alteplase)FDA Link
01/2020 - 07/2003
6Peptide Hydrolases (Proteases)FDA Link
12/2018 - 08/2006
6Platelet Membrane Glycoprotein IIbIBA
02/2016 - 10/2002
5Biomarkers (Surrogate Marker)IBA
01/2019 - 06/2004
5Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2018 - 05/2004
5Captopril (Capoten)FDA LinkGeneric
03/2007 - 08/2003
5Platelet Membrane GlycoproteinsIBA
07/2005 - 01/2002
5Abciximab (ReoPro)FDA Link
04/2005 - 11/2002
4AnticoagulantsIBA
01/2021 - 11/2005
4Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
12/2015 - 07/2003
4PAR-1 ReceptorIBA
12/2015 - 10/2012
4MetalsIBA
09/2014 - 04/2008
4Fibrinolytic Agents (Antithrombotic Agents)IBA
12/2010 - 07/2005
4Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
09/2007 - 10/2002
4Complement System Proteins (Complement)IBA
01/2007 - 02/2006
3Blood Glucose (Blood Sugar)IBA
12/2019 - 02/2009
3TicagrelorIBA
10/2019 - 04/2016
3Hypoglycemic Agents (Hypoglycemics)IBA
01/2018 - 01/2016
3omega-Chloroacetophenone (Mace)IBA
01/2018 - 04/2016
3DabigatranFDA Link
09/2013 - 11/2011
3Warfarin (Coumadin)FDA LinkGeneric
09/2013 - 08/2009
3CytokinesIBA
07/2013 - 03/2005
3StreptokinaseFDA Link
01/2011 - 07/2002
3Nitric Oxide Synthase (NO Synthase)IBA
03/2010 - 05/2004
3Creatine Kinase (Creatine Phosphokinase)IBA
01/2009 - 02/2007
3sibrafibanIBA
08/2007 - 08/2003
3Complement C5 (Complement 5)IBA
09/2006 - 08/2006
3paragonIBA
02/2003 - 07/2002
2DiureticsIBA
12/2019 - 12/2015
2Glucose (Dextrose)FDA LinkGeneric
01/2019 - 02/2009
2Hemoglobins (Hemoglobin)IBA
01/2019 - 12/2015
2Troponin T (Troponin T1)IBA
01/2018 - 02/2003
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2017 - 08/2006
22'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2017 - 07/2003
2Prasugrel HydrochlorideFDA Link
02/2016 - 04/2008
2Dipeptidyl-Peptidase IV InhibitorsIBA
01/2016 - 07/2015
2TroponinIBA
06/2015 - 07/2013
2AntithrombinsIBA
09/2013 - 04/2002
2Syndecan-1 (Syndecan 1)IBA
07/2013 - 01/2007

Therapy/Procedure

68Therapeutics
07/2021 - 01/2002
47Percutaneous Coronary Intervention
01/2021 - 10/2002
16Coronary Artery Bypass (Coronary Artery Bypass Surgery)
11/2018 - 05/2004
11Stents
11/2018 - 08/2003
9Patient Readmission
01/2018 - 01/2012
9Thrombolytic Therapy
02/2016 - 11/2002
6Secondary Prevention
12/2019 - 08/2003
5Drug-Eluting Stents
09/2014 - 09/2006
3Length of Stay
01/2018 - 02/2004
2Duration of Therapy
01/2017 - 01/2013
2Blood Transfusion (Blood Transfusions)
07/2013 - 01/2008
2Intravenous Administration
04/2011 - 01/2007